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Invitrogen
SLC4A1 Polyclonal Antibody
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Product Details
PA5-40780
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide directed towards the N-terminal of human SLC4A1 (aa 184-233).
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Amount
50 µg
Purification
Affinity Chromatography
Storage buffer
PBS with 2% sucrose
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Peptide sequence: PSQPLLPQHS SLETQLFCEQ GDGGTEGHSP SGILEKIPPD SEATLVLVGR
Sequence homology: Horse: 85%; Human: 100%; Rabbit: 85%
Target Information
The Band 3 protein is the most abundant integral protein of human erythrocyte membranes and functions as the major anion transporter polypeptide of erythrocytes. Band 3 is a 90-100 kDa protein, its microheterogeneity is ascribed mainly to the structural heterogeneity of the carbohydrate moiety. The C-terminal portion of the molecule spans the membrane several times, and is responsible for anion transport. The N-terminal portion, comprising almost half of the polypeptide chain of Band 3, is located inside the red cell and interacts with cytoskeletal and cytoplasmic proteins such as ankyrin.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: AE 1; Anion exchange protein 1; anion exchanger-1; band 3 anion exchanger; Band 3 anion transport protein; CAMP; CD233; Diego blood group; erythrocyte membrane protein band 3; erythroid anion exchange protein; Froese blood group; MGC116750; MGC116753; MGC126619; MGC126623; solute carrier family 4 (anion exchanger), member 1 (Diego blood group); Solute carrier family 4 member 1; solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group); solute carrier family 4, anion exchanger, number 1; Swann blood group; UNIMAS band 3; AE1; unnamed protein product; Waldner blood group; Wright blood group; ZNF828
Gene Aliases: AE1; BND3; CD233; CHC; DI; EMPB3; EPB3; FR; RTA1A; SAO; SLC4A1; SPH4; SW; WD; WD1; WR
UniProt ID: (Human) P02730
Entrez Gene ID: (Human) 6521
inorganic anion exchanger activity
protein binding
cytoskeletal protein binding
anion transmembrane transporter activity
bicarbonate transmembrane transporter activity
chloride transmembrane transporter activity
antiporter activity
hemoglobin binding
ankyrin binding
protein homodimerization activity
protein anchor
chloride:bicarbonate antiporter activity
ion transport
anion transport
chloride transport
cellular ion homeostasis
blood coagulation
bicarbonate transport
phospholipid scrambling
negative regulation of urine volume
pH elevation
erythrocyte development
regulation of intracellular pH
transmembrane transport
protein localization to plasma membrane
chloride transmembrane transport
negative regulation of glycolytic process through fructose-6-phosphate
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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