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SLC7A8 Polyclonal Antibody
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Product Details
OSS00266W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from internal region of human SLC7A8 (LAT2) conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in mouse and rat.
Specificity of this antibody: SLC7A8.
Target Information
SLC7A8 is sodium-independent, high-affinity transport of large neutral amino acids. It has higher affinity for L-phenylalanine than LAT1 but lower affinity for glutamine and serine. L-alanine is transported at physiological concentrations. SLC7A8 also plays a role in basolateral (re)absorption of neutral amino acids.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: cationic amino acid transporter y+ system; hLAT2; integral membrane protein E16H; L-type amino acid transporter 2; Large neutral amino acids transporter small subunit 2; mLAT2; solute carrier family 7 (amino acid transporter light chain, L system), member 8; solute carrier family 7 (amino acid transporter, L-type), member 8; solute carrier family 7 (cationic amino acid transporter, y+ system), member 8; Solute carrier family 7 member 8; solute carrier family 8 (cationic amino acid transporter, y+ system), member 7
Gene Aliases: AA408822; LAT2; Lat4; LPI-PC1; SLC7A8
UniProt ID: (Human) Q9UHI5, (Mouse) Q9QXW9, (Rat) Q9WVR6
Entrez Gene ID: (Human) 23428, (Mouse) 50934, (Rat) 84551
protein binding
organic cation transmembrane transporter activity
amino acid transmembrane transporter activity
neutral amino acid transmembrane transporter activity
L-amino acid transmembrane transporter activity
antiporter activity
toxin transporter activity
peptide antigen binding
amine transmembrane transporter activity
transporter
cellular amino acid metabolic process
transport
amino acid transport
response to toxic substance
organic cation transport
neutral amino acid transport
L-amino acid transport
leukocyte migration
metal ion homeostasis
toxin transport
L-alpha-amino acid transmembrane transport
amino acid transmembrane transport
amine transport
transmembrane transport
cation transmembrane transport
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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