MA5-15628 targets SNAI2 in WB applications and shows reactivity with Human samples.
The MA5-15628 immunogen is purified recombinant fragment of human SNAI2 expressed in E. Coli.
MA5-15628 detects SNAI2 which has a predicted molecular weight of approximately 30kDa.
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects.
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Protein Aliases: MGC10182; Neural crest transcription factor Slug; Protein snail homolog 2; SLUG; slug (chicken homolog), zinc finger protein; SLUGH1; SNAI2; snail family zinc finger 2; snail homolog 2; WS2D; Zinc finger protein SNAI2
Gene Aliases: SLUG; SLUGH; SLUGH1; SNAI2; SNAIL2; WS2D
UniProt ID: (Human) O43623
Entrez Gene ID: (Human) 6591