|Tested species reactivity||Human, Mouse, Rat|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptides RAGGPPRPMSEPGAG and NLEQRSESVRRTRSKIG, corresponding to amino acids 85-99 and 372-388 of Human SMAD6.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.5-2 µg/ml|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
PA1-29829 detects SMAD6 from mouse, human samples.
PA1-29829 has been successfully used in Western blot applications.
The PA1-29829 immunogen is: Synthetic peptides RAGGPPRPMSEPGAG and NLEQRSESVRRTRSKIG, corresponding to amino acids 85-99 and 372-388 of Human SMAD6.
Antagonist of signaling by TGF-â (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1.SMAD
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.