PA1-29829 detects SMAD6 from mouse, human samples.
PA1-29829 has been successfully used in Western blot applications.
The PA1-29829 immunogen is: Synthetic peptides RAGGPPRPMSEPGAG and NLEQRSESVRRTRSKIG, corresponding to amino acids 85-99 and 372-388 of Human SMAD6.
Antagonist of signaling by TGF-â (transforming growth factor) type 1 receptor superfamily members; has been shown to inhibit selectively BMP (bone morphogenetic proteins) signaling by competing with the co-SMAD SMAD4 for receptor-activated SMAD1.SMAD
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HsT17432; MAD homolog 6; Mad homolog 7; MADH6; MADH7; Mothers against decapentaplegic homolog 6; mothers against decapentaplegic, drosophila, homolog of, 6; mothers against DPP homolog 6; SMAD 6; SMAD family member 6; SMAD, mothers against DPP homolog 6
Gene Aliases: AOVD2; b2b390Clo; HsT17432; MADH6; MADH7; Msmad6; SMAD6
Molecular Function: transcription factor