|Tested species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptides corresponding to amino acids 22-36 and 317-331 of human SMAD8.|
|Storage buffer||PBS with 0.2% gelatin|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Western Blot (WB)||0.5-2 µg/ml|
PA1-29826 detects SMAD8 from human samples.
PA1-29826 has been successfully used in Western blot applications, where a band of 51 kDa is detected. A549 cells can be used as a positive control for this antibody.
The PA1-29826 immunogen is synthetic peptides corresponding to amino acids 22-36 and 317-331 of human SMAD8.
The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.