Recommended positive controls: HeLa, HepG2, Neuro 2A, C8D30, NIH-3T3, Raw264.7, C2C12.
Predicted reactivity: Mouse (96%), Rat (97%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
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Protein Aliases: BAF155; BRG1-associated factor 155; chromatin remodeling complex BAF155 subunit; mammalian chromatin remodeling complex BRG1-associated factor 155; SWI/SNF complex 155 kDa subunit; SWI/SNF complex subunit SMARCC1; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1; SWI3-related protein
Gene Aliases: AI115498; BAF155; CRACC1; Rsc8; SMARCC1; SRG3; SWI3
Molecular Function: chromatin/chromatin-binding, or -regulatory protein