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Bioss
SNF2L Polyclonal Antibody
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Product Details
BS-6015R
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
KLH conjugated synthetic peptide derived from human SNF2L/SMARCA1, amino acids 281-380.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Protein A
Storage buffer
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
Contains
0.02% ProClin 300
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
Target Information
Members of this G protein family are characterized by the presence of conserved SNF2 domain, a helicase-like region. They also have an ATPase activity and are thought to have a significant role regulating chromatin remodeling. Although SNF2L1 has a ubiquitous expression pattern, its active form is expressed in neurons suggesting a possible role in promoting neurite outgrowth and regulating neuronal physiology. Principal Names: SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 1 (SMARCA1); SNF2L1; SNF2LB; Possible global transcription activator SNF2L1; SWI2 Official Gene Symbol: SMARCA1 Gen Bank Accession Number: NP_620604 Gene ID: 6594 (Human) Gene Map Locus: Xq25 (Human) SNF2L1, a ~123KDa protein, is a member of SWI/SNF family of proteins.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: ATP-dependent helicase SMARCA1; DKFZp686D1623; DNA-dependent ATPase SNF2L; FLJ41547; global transcription activator homologous sequence; Nucleosome-remodeling factor subunit SNF2L; Probable global transcription activator SNF2L1; RP3-353H6.2; SNF2-like 1; sucrose nonfermenting 2-like protein 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1
Gene Aliases: 5730494M04Rik; hSNF2L; ISWI; NURF140; RGD1561046; SMARCA1; SNF2L; SNF2L1; SNF2LB; SNF2LT; SWI; SWI2
UniProt ID: (Human) P28370, (Mouse) Q6PGB8
Entrez Gene ID: (Human) 6594, (Rat) 317575, (Mouse) 93761
DNA binding
helicase activity
protein binding
ATP binding
DNA-dependent ATPase activity
nucleosome binding
annealing helicase activity
nucleosome-dependent ATPase activity
molecular_function
ATPase activity
nucleotide binding
nucleic acid binding
chromatin binding
hydrolase activity
hydrolase activity, acting on acid anhydrides
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
DNA helicase
DNA strand renaturation
chromatin remodeling
transcription, DNA-templated
brain development
covalent chromatin modification
neuron differentiation
ATP-dependent chromatin remodeling
positive regulation of transcription, DNA-templated
biological_process
metabolic process
regulation of neural precursor cell proliferation
regulation of transcription, DNA-templated
chromatin modification
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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