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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:1,000 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Non-human primate, Rat |
Host/Isotype |
Rabbit / Ig |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
A synthetic peptide from human SNIP conjugated to blue carrier protein was used as the antigen |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Storage buffer |
whole serum |
Contains |
no preservative |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
The peptide is homologous in rat and mouse.
Specificity of this antibody: SNIP.
Acts as a negative regulator of SRC by activating CSK which inhibits SRC activity and downstream signaling, leading to impaired cell spreading and migration. Regulates dendritic spine morphology. Involved in calcium-dependent exocytosis. May play a role in neurotransmitter release or synapse maintenance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: P130Cas-associated protein; p140Cap; SNAP-25-interacting protein; SNAP25-interacting protein; SNIP; SRC kinase signaling inhibitor 1
Gene Aliases: KIAA1684; mKIAA1684; P140; p140Cap; SNIP; SRCIN1
UniProt ID: (Human) Q9C0H9, (Mouse) Q9QWI6, (Rat) Q9QXY2
Entrez Gene ID: (Human) 80725, (Mouse) 56013, (Rat) 56029
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