The protein encoded by this gene associates with stem loop II of the U1 small nuclear ribonucleoprotein, which binds the 5' splice site of precursor mRNAs and is required for splicing. The encoded protein autoregulates itself by polyadenylation inhibition of its own pre-mRNA via dimerization and has been implicated in the coupling of splicing and polyadenylation.
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Protein Aliases: protein A of the U1 small nuclear RNA; SNRPA; U1 A; U1 small nuclear ribonucleoprotein A; U1 small nuclear RNP-specific A; U1 snRNP A; U1 snRNP-specific protein A; U1A
Gene Aliases: C430021M15Rik; Mud1; Rnu1a-1; Rnu1a1; SNRPA; U1-A; U1A