This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms.
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Protein Aliases: Sorting nexin-17
Gene Aliases: 5830447M19Rik; AI790646; b2b1625.1Clo; D5Ertd260e; KIAA0064; mKIAA0064; SNX17