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Proteintech
SOX21 Polyclonal Antibody
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Product Details
55052-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Peptide
Conjugate
Form
Liquid
Concentration
0.53 mg/mL
Amount
79.5 µg
Purification
Antigen affinity chromatography
Storage buffer
0.1M sodium bicarbonate/0.1M glycine, pH 7.3, with 50% glycerol, 0.1M glycine
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Target Information
The SOX gene family is defined by the Sry-related HMG box domain that mediates sequence-specific DNA binding. A variety of functions are associated with the SOX proteins during development. The highly complex group of Sox genes cluster at least 40 different loci that rapidly diverged in various animal lineages. At present, 30 Sox genes have been identified. Members of this family have been shown to be conserved during evolution and to play key roles during animal development. SOX21 may play a role as an activator of transcription of OPRM1. Overexpression of SOX21 can cause an up-regulation of the OPRM1 distal promoter in mor-expressing neuronal cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: DNA-binding protein SOX21; HMG-box protein SOX21; SOX-A; SOX25SOX-A; soxA; SRY (sex determining region Y)-box 21; SRY-box 21; SRY-box containing gene 21; Transcription factor SOX-21
Gene Aliases: SOX21; SOX25; SOXA
UniProt ID: (Human) Q9Y651, (Mouse) Q811W0
Entrez Gene ID: (Human) 11166, (Mouse) 223227
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
DNA binding
transcription factor activity, sequence-specific DNA binding
HMG box transcription factor
negative regulation of transcription from RNA polymerase II promoter
hair follicle development
regulation of transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
brain development
neuron differentiation
developmental process
hair cycle
skin development
positive regulation of transcription from RNA polymerase II promoter
stem cell differentiation
transcription, DNA-templated
negative regulation of neuron differentiation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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