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Invitrogen
SP7 Polyclonal Antibody
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FIGURE: 1 / 19
SP7 Antibody (PA5-115697) in IHC (P)
Immunohistochemistry analysis of SP7 in human normal tissues adjacent to colorectal cancer. Samples were treated with formaldehyde and treated with citrate buffer for antigen retrieval, blocked, and incubated (1.5 hours at 22°C) with polyclonal antibody (Product # PA5-115697) at a dilution of 1:100. Secondary staining was applied with HRP conjugated anti-Rabbit.
Product Details
PA5-115697
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
C. elegans,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SP7(Accession Q8TDD2), corresponding to amino acid residues T397-I431.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Purification
Affinity chromatography
Storage buffer
PBS with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total osterix.
Target Information
SP7 is a C2H2-type zinc finger transcription factor of the SP gene family and a putative master regulator of bone cell differentiation (Gao et al., 2004 [PubMed 15474293]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: C22; MGC126598; osterix; trans-acting transcription factor 7; Transcription factor Sp7; Zinc finger protein osterix
Gene Aliases: 6430578P22Rik; C22; OI11; OI12; osterix; OSX; SP7
UniProt ID: (Human) Q8TDD2, (Mouse) Q8VI67
Entrez Gene ID: (Human) 121340, (Mouse) 170574, (Rat) 300260
osteoblast differentiation
transcription, DNA-templated
regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase II promoter
hematopoietic stem cell differentiation
positive regulation of stem cell differentiation
regulation of transcription, DNA-templated
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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