Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
SPR Fusion Protein Ag10395 (1-261 aa encoded by BC017310) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.3 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Immunogen sequence: MEGGLGRAV CLLTGASRGF GRTLAPLLAS LLSPGSVLVL SARNDEALRQ LEAELGAERS GLRVVRVPAD LGAEAGLQQL LGALRELPRP KGLQRLLLIN NAGSLGDVSK GFVDLSDSTQ VNNYWALNLT SMLCLTSSVL KAFPDSPGLN RTVVNISSLC ALQPFKGWAL YCAGKAARDM LFQVLALEEP NVRVLNYAPG PLDTDMQQLA RETSVDPDMR KGLQELKAKG KLVDCKVSAQ KLLSLLEKDE FKSGAHVDFY DK (1-261 aa encoded by BC017310)
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR
Gene Aliases: AA409688; ENSMUSG00000071345; Gm10328; SDR38C1; SPR
UniProt ID: (Human) P35270, (Rat) P18297
Entrez Gene ID: (Human) 6697, (Mouse) 20751, (Rat) 29270
Molecular Function:
oxidoreductase
reductase
metabolite interconversion enzyme
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