Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant fragment corresponding to a region within amino acids 65 and 261 of SPR (Uniprot ID#P35270) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
0.1M tris glycine, pH 7, with 20% glycerol |
Contains |
0.01% thimerosal |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_11153773 |
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2.
Predicted reactivity: Rabbit (86%), Rhesus Monkey (97%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR
Gene Aliases: AA409688; ENSMUSG00000071345; Gm10328; SDR38C1; SPR
UniProt ID: (Human) P35270
Entrez Gene ID: (Human) 6697, (Mouse) 20751
Molecular Function:
oxidoreductase
reductase
metabolite interconversion enzyme
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