Applications | Tested Dilution | Publications |
---|---|---|
Western Blot (WB) |
0.1-0.5 µg/mL | - |
Product Specifications | |
---|---|
Species Reactivity |
Human, Mouse |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
E. coli-derived human SPR recombinant protein (Position: V36-K261). |
Conjugate |
Unconjugated |
Form |
Lyophilized |
Concentration |
500 µg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS with 4mg trehalose |
Contains |
0.05mg sodium azide |
Storage conditions |
-20°C |
RRID |
AB_2747183 |
Add 0.2 mL of distilled water, will yield a concentration of 500 µg/mL.
SPR encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sepiapterin reductase; short chain dehydrogenase/reductase family 38C, member 1; SPR
Gene Aliases: AA409688; ENSMUSG00000071345; Gm10328; SDR38C1; SPR
UniProt ID: (Human) P35270
Entrez Gene ID: (Human) 6697, (Mouse) 20751
Molecular Function:
oxidoreductase
reductase
metabolite interconversion enzyme
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