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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SPRED2 Antibodies

          Proteintech

          SPRED2 Polyclonal Antibody

          4 References
          View all (8) SPRED2 antibodies

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          Cite SPRED2 Polyclonal Antibody

          • Antibody Testing Data (7)
          SPRED2 Antibody in Immunocytochemistry (ICC/IF)
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          SPRED2 Antibody in Immunocytochemistry (ICC/IF)
          Group 53 Created with Sketch.

          FIGURE: 1 / 7

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          SPRED2 Antibody (24091-1-AP) in ICC/IF

          Immunofluorescent analysis of ( -20°C Ethanol ) fixed HeLa cells using 24091-1-AP (SPRED2 antibody) at dilution of 1:50 and Alexa Fluor 488-conjugated AffiniPure Goat Anti-Rabbit IGG (H+L). {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          SPRED2 Antibody in Immunocytochemistry (ICC/IF)
          SPRED2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SPRED2 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          SPRED2 Antibody in Western Blot (WB)
          SPRED2 Antibody in Western Blot (WB)
          SPRED2 Antibody in Western Blot (WB)
          SPRED2 Antibody in Western Blot (WB)
          SPRED2 Polyclonal Antibody

          Product Details

          24091-1-AP

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:500-1:2,000
          View 2 publications 2 publications

          Immunohistochemistry (IHC)

          -
          View 1 publication 1 publication

          Immunohistochemistry (Paraffin) (IHC (P))

          1:20-1:200
          -

          Immunocytochemistry (ICC/IF)

          1:50-1:500
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / IgG

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          SPRED2 Fusion Protein Ag21359 (122-214 aa encoded by BC136334)
          View immunogen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Liquid

          Concentration

          0.13 mg/mL

          Purification

          Antigen affinity chromatography

          Storage buffer

          PBS, pH 7.3, with 50% glycerol

          Contains

          0.02% sodium azide

          Storage conditions

          -20°C

          Shipping conditions

          Wet ice (domestic); Dry ice (international)

          Product Specific Information

          Immunogen sequence: LIEGSTTSS STIHNEAELG DDDVFTTATD SSSNSSQKRE QPTRTISSPT SCEHRRIYTL GHLHDSYPTD HYHLDQPMPR PYRQVSFPDD DEEI (122-214 aa encoded by B C136334)

          Target Information

          SPRED2 is a member of the Sprouty /SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (Nonami et al., 2004 ).

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: Spred-2; sprouty protein with EVH-1 domain 2, related sequence; sprouty related, EVH1 domain containing 2; sprouty-related, EVH1 domain containing 2; Sprouty-related, EVH1 domain-containing protein 2

          View more View less

          Gene Aliases: C79158; Spred-2; SPRED2

          View more View less

          UniProt ID: (Human) Q7Z698, (Mouse) Q924S7, (Rat) Q3C2P8

          View more View less

          Entrez Gene ID: (Human) 200734, (Mouse) 114716, (Rat) 305539

          View more View less

          Function(s)
          stem cell factor receptor binding protein binding protein kinase binding protein serine/threonine kinase inhibitor activity scaffold/adaptor protein
          Process(es)
          inactivation of MAPK activity multicellular organism development fibroblast growth factor receptor signaling pathway negative regulation of peptidyl-threonine phosphorylation positive regulation of DNA damage response, signal transduction by p53 class mediator regulation of protein deacetylation regulation of signal transduction negative regulation of protein serine/threonine kinase activity
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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