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Proteintech
SPRED2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
24091-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SPRED2 Fusion Protein Ag21359 (122-214 aa encoded by BC136334)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: LIEGSTTSS STIHNEAELG DDDVFTTATD SSSNSSQKRE QPTRTISSPT SCEHRRIYTL GHLHDSYPTD HYHLDQPMPR PYRQVSFPDD DEEI (122-214 aa encoded by B C136334)
Target Information
SPRED2 is a member of the Sprouty /SPRED family of proteins that regulate growth factor-induced activation of the MAP kinase cascade (Nonami et al., 2004 ).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: EVH1/Sprouty domain containing protein; spred-2; sprouty protein with EVH-1 domain 2, related sequence; unnamed protein product
Gene Aliases: NS14; Spred-2
UniProt ID: (Human) Q7Z698, (Mouse) Q924S7, (Rat) Q3C2P8
Entrez Gene ID: (Human) 200734, (Mouse) 114716, (Rat) 305539
regulation of signal transduction
negative regulation of epithelial to mesenchymal transition
negative regulation of transforming growth factor beta receptor signaling pathway
negative regulation of MAPK cascade
positive regulation of DNA damage response, signal transduction by p53 class mediator
negative regulation of ERK1 and ERK2 cascade
negative regulation of intracellular signal transduction
negative regulation of lens fiber cell differentiation
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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