Proteintech

SPTBN1 Polyclonal Antibody

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SPTBN1 Antibody in Immunohistochemistry (Paraffin) (IHC (P)) — Immunohistochemistry of paraffin-embedded human kidney using 19722-1-AP (SPTBN1-Specific antibody) at dilution of 1:100 (under 40x lens).

SPTBN1 Antibody in Western Blot (WB) — Mouse kidney tissue were subjected to SDS PAGE followed by western blot with 19722-1-AP (SPTBN1-Specific antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours.

SPTBN1 Antibody in Immunoprecipitation (IP) — IP result of anti-SPTBN1-Specific (IP:19722-1-AP, 5ug; Detection:19722-1-AP 1:600) with HEK-293 cells lysate 1000ug.

Product Details

19722-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 2 publications 2 publications
Immunohistochemistry (IHC)	-	View 1 publication 1 publication
Immunohistochemistry (Paraffin) (IHC (P))	1:20-1:200	-
Immunocytochemistry (ICC/IF)	-	View 1 publication 1 publication
Immunoprecipitation (IP)	0.5-4.0 µg	View 1 publication 1 publication

Product Specifications
Species Reactivity	Human, Mouse
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Peptide
Conjugate	Unconjugated
Form	Liquid
Concentration	0.17 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Target Information

Spectrin (Sp), the most abundant of the erythrocyte membrane skeleton proteins, helps these cells maintain their characteristic biconcave shape while remaining flexible and elastic. Erythrocyte Sp is a heterodimer composed of a 280 kDa alpha subunit and a 246 kDa beta subunit which associate in a side-to-side, antiparallel configuration to form a 100 nm rod-like structure. Sp in other tissues may be composed of distinct but homologous alpha and beta subunits, sometimes referred to as fodrin. A newly introduced nomenclature designates the Sp subunits of the erythrocyte as alpha-1 and beta-1, and the fodrin subunits as alpha-2 and beta-2. Alternatively spliced forms of each are designated as epsilon-1, epsilon-2, etc. (e. g. beta-1 epsilon-1).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

USP9X regulates centrosome duplication and promotes breast carcinogenesis.

Nature communications

Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L

Fri Mar 31 00:00:00 EDT 2017

USP9X regulates centrosome duplication and promotes breast carcinogenesis.

Nature communications

Li X,Song N,Liu L,Liu X,Ding X,Song X,Yang S,Shan L,Zhou X,Su D,Wang Y,Zhang Q,Cao C,Ma S,Yu N,Yang F,Wang Y,Yao Z,Shang Y,Shi L

Fri Mar 31 00:00:00 EDT 2017

Identification of nuclear phosphoproteins as novel tobacco markers in mouse lung tissue following short-term exposure to tobacco smoke.

FEBS open bio

Niimori-Kita K,Ogino K,Mikami S,Kudoh S,Koizumi D,Kudoh N,Nakamura F,Misumi M,Shimomura T,Hasegawa K,Usui F,Nagahara N,Ito T

Tue Oct 28 00:00:00 EDT 2014

Global profiling of proteolytically modified proteins in human metastatic hepatocellular carcinoma cell lines reveals CAPN2 centered network.

Proteomics

Shen C,Yu Y,Li H,Yan G,Liu M,Shen H,Yang P

Fri Jun 01 00:00:00 EDT 2012

Global profiling of proteolytically modified proteins in human metastatic hepatocellular carcinoma cell lines reveals CAPN2 centered network.

Proteomics

Shen C,Yu Y,Li H,Yan G,Liu M,Shen H,Yang P

Fri Jun 01 00:00:00 EDT 2012

Bioinformatics

Protein Aliases: beta fodrin; beta-fodrin; beta-G spectrin; Beta-II spectrin; beta-spectrin 2; beta-spectrin 2, non-erythrocytic; beta-spectrin II; beta-spectrin non-erythrocytic 1; brain spectrin; embryonic liver beta-fodrin; Embryonic liver fodrin; embryonic liver fodrin beta chain; epididymis luminal protein 102; Fodrin beta chain; non-erythrocytic; spectrin beta 2; spectrin beta chain, brain 1; Spectrin beta chain, non-erythrocytic 1; spectrin G; spectrin, beta, non-erythrocytic 1; Spectrin, non-erythroid beta chain 1

Gene Aliases: 9930031C03Rik; AL033301; betaSpII; ELF; elf1; elf3; HEL102; mKIAA4049; Spnb-2; Spnb2; SPTB2; SPTBN1

UniProt ID: (Human) Q01082, (Mouse) Q62261

Entrez Gene ID: (Human) 6711, (Mouse) 20742

Function(s)