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Product Details
18931-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
SPZ1 Fusion Protein Ag6995 (1-430 aa encoded by BC033798)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MASSAKSAE MPTISKTLNP TPDPHQEYLD PRITIALFEI GSHSPSSWGS LPFLKNSSHQ VTEQQTAQKF NNLLKEIKDI LKNMAGFEEK ITEAKELFEE TNITEDVSAH KENIRGLDKI NEMLSTNLPV SLAPEKEDNE KKQEMILETN ITEDVSAHKE NIRGLDKINE MLSTNLPVSL APEKEDNEKK QQMIMENQNS ENTAQVFARD LVNRLEEKKV LNETQQSQEK AKNRLNVQEE TMKIRNNMEQ LLQEAEHWSK QHTELSKLIK SYQKSQKDIS ETLGNNGVGF QTQPNNEVSA KHELEEQVKK LSHDTYSLQL MAALLENECQ ILQQRVEILK ELHHQKQGTL QEKPIQINYK QDKKNQKPSE AKKVEMYKQN KQAMKGTFWK KDRSCRSLDV CLNKKACNTQ FNIHVARKAL RGKMRSASSL R (1-430 aa encoded by BC033798)
Target Information
Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: protein phosphatase 1, regulatory subunit 148; Spermatogenic leucine zipper protein 1; spermatogenic zip 1; testis secretory sperm-binding protein Li 232m; Testis-specific protein 1; Testis-specific protein NYD-TSP1
Gene Aliases: NYD-TSP1; PPP1R148; SPZ1; TSP1
UniProt ID: (Human) Q9BXG8
Entrez Gene ID: (Human) 84654
Molecular Function:
basic leucine zipper transcription factor
DNA-binding transcription factor
gene-specific transcriptional regulator
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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