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Invitrogen
SPZ1 Polyclonal Antibody
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FIGURE: 1 / 2
SPZ1 Antibody (PA5-23391) in IHC (P)
Immunohistochemistry analysis of SPZ1 in formalin-fixed, paraffin-embedded mouse testis tissue. Samples were incubated with SPZ1 polyclonal antibody (Product # PA5-23391) using a dilution of 5 µg/mL. Isotype control (top left) and this antibody (bottom left, right).
Product Details
PA5-23391
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A portion of amino acids 40-90 of human SPZ1.
Conjugate
Form
Liquid
Concentration
0.5 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS with 0.05% BSA
Contains
0.05% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
The amino acid sequence used as immunogen is 82% homologous in Chicken.
Target Information
Spermatogenic leucine zipper protein 1 is a member of the basic helix-loop-helix (bHLH) family of transcription factors which is expressed specifically in the testis and epididymis. Studies show that SPZ1 acts downstream of mitogen-activated protein kinase (MAPK), an extracellular signal-regulated kinase 1/2 to up-regulate cell proliferation and tumorigenesis. Also, through an interaction with proliferating cell nuclear antigen (PCNA) promoter, SPZ1 induced cell proliferation concomitant with an increase in PCNA gene expression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: BHLH-Zip transcription factor SPZ1; protein phosphatase 1, regulatory subunit 148; Spermatogenic leucine zipper protein 1; Spermatogenic Zip 1; testis secretory sperm-binding protein Li 232m; Testis-specific protein 1; Testis-specific protein NYD-TSP1
Gene Aliases: 1700027M20Rik; AI429130; NYD-TSP1; PPP1R148; SPZ1; TSP1
UniProt ID: (Human) Q9BXG8, (Mouse) Q99MY0, (Rat) Q6AXY9
Entrez Gene ID: (Human) 84654, (Mouse) 79401, (Rat) 499510
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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