PA5-28263 targets SREBF2 in IF and WB applications and shows reactivity with Human samples.
The PA5-28263 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 480 of Human SREBF2.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.
This gene encodes a ubiquitously expressed transcription factor that controls cholesterol homeostasis by stimulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain.
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Protein Aliases: bHLHd2; Class D basic helix-loop-helix protein 2; Processed sterol regulatory element-binding protein 2; SREBP-2; SREBP2; Sterol regulatory element-binding protein 2; Sterol regulatory element-binding transcription factor 2
Gene Aliases: BHLHD2; SREBF2; SREBP-2; SREBP2
UniProt ID: (Human) Q12772
Entrez Gene ID: (Human) 6721