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          Disclaimer

          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

          • Primary Antibodies ›
          • SRF Antibodies

          Osenses

          SRF Polyclonal Antibody

          1 Reference
          View all (29) SRF antibodies

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          Cite SRF Polyclonal Antibody

          • Antibody Testing Data (1)
          SRF Antibody in Western Blot (WB)
          Group 53 Created with Sketch.
          SRF Antibody in Western Blot (WB)
          Group 53 Created with Sketch.

          FIGURE: 1 / 1

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          SRF Antibody (OSS00428W-100UL) in WB

          WB on rat tissue lysates. Blocking: 1% LFDM for 30 min at RT; primary antibody: dilution 1:1000 incubated at 4°C overnight. {{ $ctrl.currentElement.advancedVerification.fullName }} validation info. View more
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          View Product

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          SRF Antibody in Western Blot (WB)

          Product Details

          OSS00428W-100UL

          Applications
          Tested Dilution
          Publications

          Western Blot (WB)

          1:1,000
          -

          Immunohistochemistry (IHC)

          1:1,000
          -

          Miscellaneous PubMed (Misc)

          -
          View 1 publication 1 publication
          Product Specifications

          Species Reactivity

          Human, Mouse, Rat

          Host/Isotype

          Rabbit / Ig

          Class

          Polyclonal

          Type

          Antibody

          Immunogen

          A synthetic peptide from human SRF conjugated to blue carrier protein was used as the antigen

          Conjugate

          Unconjugated Unconjugated Unconjugated

          Form

          Lyophilized

          Concentration

          Conc. Not Determined

          Storage buffer

          whole serum

          Contains

          no preservative

          Storage conditions

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.

          Shipping conditions

          Ambient (domestic); Wet ice (international)

          Product Specific Information

          Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.

          The peptide is homologous in rat and mouse.

          Specificity of this antibody: SRF.

          Target Information

          Serum response factor (SRF) is a transcription factor that binds the serum response element (SRE), a sequence that mediates the transient response of many cellular genes to growth stimulation. SRF-binding sites are also constitutive promotor elements in many muscle-specific promotors. SFR is required for cardiac differentiation and maturation.

          For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

          Bioinformatics

          Protein Aliases: c-fos serum response element-binding transcription factor; minichromosome maintenance 1 homolog; OTTHUMP00000039820; Serum response factor; serum response factor (c-fos serum response element-binding transcription factor); SRF

          View more View less

          Gene Aliases: AW049942; AW240594; MCM1; RGD1559787; SRF

          View more View less

          UniProt ID: (Human) P11831, (Mouse) Q9JM73

          View more View less

          Entrez Gene ID: (Human) 6722, (Mouse) 20807, (Rat) 501099

          View more View less

          Function(s)
          RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, RNA polymerase II core promoter sequence-specific transcription factor activity, RNA polymerase II transcription factor binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding transcription factor activity, sequence-specific DNA binding transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding protein binding transcription factor binding serum response element binding chromatin DNA binding protein homodimerization activity histone deacetylase binding primary miRNA binding DNA binding chromatin binding sequence-specific DNA binding protein dimerization activity
          Process(es)
          patterning of blood vessels response to hypoxia mesoderm formation neuron migration trophectodermal cell differentiation heart looping morphogenesis of an epithelial sheet cell migration involved in sprouting angiogenesis positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation transcription from RNA polymerase II promoter cell-matrix adhesion heart development long-term memory negative regulation of cell proliferation associative learning response to toxic substance response to hormone epithelial structure maintenance positive regulation of transcription via serum response element binding hippocampus development tangential migration from the subventricular zone to the olfactory bulb regulation of cell adhesion platelet activation platelet formation negative regulation of cell migration thyroid gland development neuron projection development regulation of water loss via skin response to cytokine megakaryocyte development dorsal aorta morphogenesis mRNA transcription from RNA polymerase II promoter stress fiber assembly skin morphogenesis positive thymic T cell selection sarcomere organization positive regulation of cell differentiation positive regulation of axon extension positive regulation of transcription from RNA polymerase II promoter positive regulation of smooth muscle contraction positive regulation of transcription by glucose muscle cell cellular homeostasis thymus development developmental growth neuron development erythrocyte development positive regulation of sequence-specific DNA binding transcription factor activity regulation of smooth muscle cell differentiation positive regulation of filopodium assembly cardiac myofibril assembly angiogenesis involved in wound healing hematopoietic stem cell differentiation positive regulation of transcription initiation from RNA polymerase II promoter long term synaptic depression face development heart trabecula formation lung morphogenesis bronchus cartilage development trachea cartilage development cardiac vascular smooth muscle cell differentiation eyelid development in camera-type eye lung smooth muscle development bicellular tight junction assembly cellular response to glucose stimulus primitive streak formation epithelial cell-cell adhesion cellular senescence negative regulation of beta-amyloid clearance negative regulation of pri-miRNA transcription from RNA polymerase II promoter positive regulation of pri-miRNA transcription from RNA polymerase II promoter in utero embryonic development leukocyte differentiation transcription, DNA-templated regulation of transcription, DNA-templated actin filament organization multicellular organism development gastrulation single organismal cell-cell adhesion actin cytoskeleton organization contractile actin filament bundle assembly positive regulation of transcription, DNA-templated
          It has to be done as per old AB suggested Products section.
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          If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

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