Sequence of this protein is as follows: LCCQGECQWL HLDLIKEMRQ FCQSLFPVVA YAYCTIPTYP SGQIGFMLCS KNPSTNFQEP VQPLTQQQVA QMQLKYYNSD VHRAAFVLPE FARKALNDV
The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. SRM synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Putrescine aminopropyltransferase; SPDSY; Spermidine synthase; spermidine synthase-1
Gene Aliases: PAPT; SPDSY; SPS1; SRM; SRML1
UniProt ID: (Human) P19623
Entrez Gene ID: (Human) 6723
Molecular Function: transferase