Immunogen sequence: MVLLESEQFL TELTRLFQKC RTSGSVYITL KKYDGRTKPI PKKGTVEGFE PADNKCLLRA TDGKKKISTV VSSKEVNKFQ MAYSNLLRAN MDGLKKRDKK NKTKKTKAAA AAAAAAPAAA ATAPTTAATT AATAAQ; Positive Samples: HeLa, 22RV1, HT-29, HepG2, A-549; Cellular Location: Cytoplasm
Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding.
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Protein Aliases: (homologous Alu RNA binding protein); 18 kDa Alu RNA-binding protein; homologous Alu RNA binding protein; homologous Alu RNA-binding protein; Signal recognition particle 14 kDa protein; signal recognition particle 14kDa (homologous Alu RNA binding protein); SRP14
Gene Aliases: 14kDa; ALURBP; AW536328; SRP14