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Invitrogen
SRPK1 Polyclonal Antibody
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Product Details
PA5-101867
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthesized peptide derived from human SRPK1(Accession Q96SB4), corresponding to amino acid residues K575-G625.
Conjugate
Form
Liquid
Concentration
1 mg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS, pH 7.4, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Antibody detects endogenous levels of total SRPK1.
Target Information
SRPK1 is a serine/threonine kinase that plays a role in the regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. SRPK1 localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: OTTHUMP00000016277; serine/arginine-rich protein specific kinase 1; Serine/arginine-rich protein-specific kinase 1; serine/arginine-rich splicing factor kinase 1; serine/threonine-protein kinase SRPK1; SFRS protein kinase 1; SR protein-specific kinase 1; SR-protein-specific kinase 1; srpk1; SRSF protein kinase 1; unnamed protein product
Gene Aliases: AU017960; SFRSK1; SRPK1
UniProt ID: (Human) Q96SB4, (Mouse) O70551
Entrez Gene ID: (Human) 6732, (Mouse) 20815, (Rat) 361811
nucleotide binding
magnesium ion binding
RNA binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
transferase activity
protein serine kinase activity
transferase activity, transferring phosphorus-containing groups
poly(A) RNA binding
non-receptor serine/threonine protein kinase
spliceosomal complex assembly
mRNA processing
protein phosphorylation
chromosome segregation
RNA splicing
cell differentiation
sperm chromatin condensation
intracellular signal transduction
positive regulation of viral genome replication
negative regulation of viral genome replication
innate immune response
regulation of mRNA splicing, via spliceosome
regulation of mRNA processing
phosphorylation
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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