This Antibody was verified by KnockDown to ensure that the antibody binds to the antigen stated. View Details
PA5-30220 targets SF2 in IF, IHC (P), and WB applications and shows reactivity with Human and mouse samples.
The PA5-30220 immunogen is recombinant fragment corresponding to a region within amino acids 1 and 224 of Human SF2.
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This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Alternative-splicing factor 1; arginine/serine-rich 1; ASF-1; ASF/SF2; P33 subunit; pre-mRNA-splicing factor SF2; pre-mRNA-splicing factor SF2, P33 subunit; Pre-mRNA-splicing factor SRp30a; Serine/arginine-rich splicing factor 1; SF2; SF2p33; SFRS1; splicing factor; splicing factor 2; Splicing factor, arginine/serine-rich 1; splicing factor, arginine/serine-rich 1 (ASF/SF2); splicing factor, arginine/serine-rich, 30-KD, A; SR splicing factor 1; SRp30a
Gene Aliases: 1110054N12Rik; 5730507C05Rik; 6330415C05Rik; AI482334; ASF; AW491331; OK/SW-cl.3; SF2; SF2P33; SFRS1; SRp30a; SRSF1