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Invitrogen
SSTR1 Polyclonal Antibody
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Product Details
PA3-108
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Published species
C. elegans,
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synthetic peptide corresponding to residues C(380) R N G T C T S R I T T L(391) of human SSTR1.
Conjugate
Form
Liquid
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
0.05% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
PA3-108 detects the Somatostatin Receptor 1 in human samples.
PA3-108 has been used successfully in Western blot, immunocytochemistry, and immunohistochemistry procedures. In Western blot analysis of SSTR1 transfected HEK-293 cells this antibody detects a ~52-63 kDa protein representing SSTR1.
The PA3-108 immunogen is a synthetic peptide corresponding to residues C(380) R N G T C T S R I T T L(391) of human SSTR1.
Target Information
Somatostatin acts to regulate numerous physiological processes by binding to and activating specific receptors in target tissues. Activation of these receptors by somatostatin, which is secreted by nerve and endocrine cells, regulates the secretion of insulin, glucagon and growth hormone, neuronal excitability in both the brain and the peripheral nervous system, and cell growth. Somatostatin receptors have been implicated in numerous diseases ranging from Alzheimer's to cancers of the gastrointestinal tract, breast, prostate, and pituitary.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: somatostatin receptor; Somatostatin receptor type 1; SRIF-2; SS-1-R; Sst1 receptor
Gene Aliases: SRIF-2; SS-1-R; SS1-R; SS1R; SSTR1
UniProt ID: (Human) P30872
Entrez Gene ID: (Human) 6751
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
glutamate receptor signaling pathway
neuropeptide signaling pathway
cell-cell signaling
chemical synaptic transmission
spermatogenesis
response to nutrient
digestion
negative regulation of cell proliferation
cerebellum development
forebrain development
somatostatin signaling pathway
response to starvation
cellular response to estradiol stimulus
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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