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Invitrogen
ST5 Polyclonal Antibody
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FIGURE: 1 / 1
ST5 Antibody (PA5-95166) in WB
Western blot analysis of ST5 in Lane 1: rat testis tissue lysate (40 µg), Lane 2: A431 whole cell lysate (40 µg), Lane 3: HeLa whole cell lysate (40 µg), Lane 4: COLO320 whole cell lysate (40 µg), Lane 5: NIH whole cell lysate (40 µg). Samples were incubated with ST5 polyclonal antibody (Product # PA5-95166).
Product Details
PA5-95166
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human ST5 (571-586aa KRHSHDDMLLLAQLSL).
Conjugate
Form
Lyophilized
Concentration
500 µg/mL
Amount
100 µg
Purification
Affinity chromatography
Storage buffer
PBS with 5mg BSA
Contains
0.05mg sodium azide, 0.05mg thimerosal
Storage conditions
-20°C
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: Rat Testis Tissue, A431 whole cell, HELA whole cell, COLO320 whole cell, NIH/3T3 whole cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Target Information
This gene was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. The protein encoded by this gene contains a C-terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c-Abl kinase, and acts as a regulator of MAPK1/ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three alternatively spliced transcript variants of this gene encoding distinct isoforms are identified.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DENN domain-containing protein 2B; DENN/MADD domain containing 2B; HeLa tumor suppression 1; p70; Suppression of tumorigenicity 5 protein; unnamed protein product
Gene Aliases: 2010004M01Rik; 2610305K15Rik; Denn2b; DENND2B; HTS1; p126; ST5
UniProt ID: (Human) P78524, (Mouse) Q924W7
Entrez Gene ID: (Human) 6764, (Mouse) 76954, (Rat) 308944
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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