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Product Details
20392-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STAC3 Fusion Protein Ag14232 (40-364 aa encoded by BC008069)
Conjugate
Unconjugated
Form
Liquid
Concentration
0.29 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Product Specific Information
Immunogen sequence: MELPPEPQA NGEAVGAGGG PIYYIYEEEE EEEEEEEEPP PEPPKLVNDK PHKFKDHFFK KPKFCDVCAR MIVLNNKFGL RCKNCKTNIH EHCQSYVEMQ RCFGKIPPGF HRAYSSPLYS NQQYACVKDL SAANRNDPVF ETLRTGVIMA NKERKKGQAD KKNPVAAMME EEPESARPEE GKPQDGNPEG DKKAEKKTPD DKHKQPGFQQ SHYFVALYRF KALEKDDLDF PPGEKITVID DSNEEWWRGK IGEKVGFFPP NFIIRVRAGE RVHRVTRSFV GNREIGQITL KKDQIVVQKG DEAGGYVKVY TGRKVGLFPT DFLEEI (40-364 aa encoded by BC008069)
Target Information
The Src homology 3 (SH3) domain is a highly conserved 60 amino acid protein domain that is organized into a beta-barrel fold consisting of five or six beta strands arranged as two tightly packed anti-parallel beta sheets. This domain is found in proteins that mediate assembly of specific protein complexes and interact with other proteins, specifically recognizing proline-rich regions. STAC3 (SH3 and cysteine rich domain 3) is a 364 amino acid protein containing one phorbol-ester/DAG-type zinc finger and two SH3 (Src homology 3) domains. Existing as two alternatively spliced isoforms, STAC3 maps to human chromosome 12q13.3. Human chromosome 12 encodes over 1,400 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: SH3 and cysteine-rich domain-containing protein 3
Gene Aliases: 9830125E18; NAM; STAC3
UniProt ID: (Human) Q96MF2, (Mouse) Q8BZ71
Entrez Gene ID: (Human) 246329, (Mouse) 237611, (Rat) 362895
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