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Invitrogen
STAM2 Polyclonal Antibody
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Product Details
PA5-121061
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 376-525 of human STAM2 (NP_005834.4).
Conjugate
Form
Liquid
Concentration
1.27 mg/mL
Purification
Affinity Chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Positive test controls include: MCF7, HepG2, OVCAR3, PC-3. The target is usually found in the following locations: Cytoplasm, Cytoplasmic side, Early endosome membrane, Peripheral membrane protein.
Immunogen sequence: KLHPPAHYPP ASSGVPMQTY PVQSHGGNYM GQSIHQVTVA QSYSLGPDQI GPLRSLPPNV NSSVTAQPAQ TSYLSTGQDT VSNPTYMNQN SNLQSATGTT AYTQQMGMSV DMSSYQNTTS NLPQLAGFPV TVPAHPVAQQ HTNYHQQPLL
Target Information
The protein encoded by this gene is closely related to STAM, an adaptor protein involved in the downstream signaling of cytokine receptors, both of which contain a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). Similar to STAM, this protein acts downstream of JAK kinases, and is phosphorylated in response to cytokine stimulation. This protein and STAM thus are thought to exhibit compensatory effects on the signaling pathway downstream of JAK kinases upon cytokine stimulation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp564C047; HGNC:11358; Hrs binding protein; Hrs-binding protein; HSE1 homolog; Signal transducing adapter molecule 2; signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; STAM-2; STAM-like protein containing SH3 and ITAM domains 2
Gene Aliases: 1200004O12Rik; 5730456G07Rik; BB145015; HBP; STAM2; STAM2A; STAM2B
UniProt ID: (Human) O75886, (Rat) Q5XHY7, (Mouse) O88811
Entrez Gene ID: (Human) 10254, (Rat) 311030, (Mouse) 56324
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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