This gene encodes a member of the AGC serine/threonine kinase family of proteins. The kinase activity of this protein is regulated by autophosphorylation and phosphorylation by other upstream kinases. This protein has been shown to function in the cell cycle and apoptosis. This protein has also been found to regulate the protein stability and transcriptional activity of the MYC oncogene. Alternative splicing results in multiple transcript variants.
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Protein Aliases: Ndr Ser/Thr kinase-like protein; NDR1 protein kinase; NDR2 protein kinase; nuclear Dbf2-related 2; Nuclear Dbf2-related kinase 1; Nuclear Dbf2-related kinase 2; serine/threonine kinase 38-like; Serine/threonine-protein kinase 38; Serine/threonine-protein kinase 38-like; stk38; STK38L
Gene Aliases: 4930473A22Rik; 5830476G13Rik; 9530097A09Rik; AA617404; B230328I19; KIAA0965; NDR; NDR1; NDR2; Ndr54; RGD1564793; STK38; STK38L
Molecular Function: annexin calcium-binding protein calmodulin intracellular calcium-sensing protein kinase non-receptor serine/threonine protein kinase protein kinase transfer/carrier protein transferase