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Proteintech
STMN2 Polyclonal Antibody
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Product Details
10586-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
STMN2 Fusion Protein Ag0929 (1-179 aa encoded by BC006302)
Conjugate
Form
Liquid
Concentration
0.18 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MAKTAMAYK EKMKELSMLS LICSCFYPEP RNINIYTYDD MEVKQINKRA SGQAFELILK PPSPISEAPR TLASPKKKDL SLEEIQKKLE AAEERRKSQE AQVLKQLAEK REHEREVLQK ALEENNNFSK MAEEKLILKM EQIKENREAN LAAIIERLQE KERHAAEVRR NKELQVELSG (1-179 aa encoded by BC006302)
Target Information
STMN2, also known as SCG-10, is a neuronal growth-associated protein that shares significant amino acid sequence similarity with the phosphoprotein stathmin. STMN2 may play a role in neuronal differentiation, and in modulating membrane interaction with the cytoskeleton during neurite outgrowth. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: neuron-specific growth-associated protein; neuronal growth-associated protein (silencer element); Protein SCG10; SGC10; Stathmin-2; stathmin-like 2; superior cervical ganglia, neural specific 10; Superior cervical ganglion-10 protein; superiorcervical ganglia, neural specific 10
Gene Aliases: AI159727; SCG10; SCGN10; Stmb2; STMN2
UniProt ID: (Human) Q93045, (Rat) P21818, (Mouse) P55821
Entrez Gene ID: (Human) 11075, (Rat) 84510, (Mouse) 20257
negative regulation of microtubule depolymerization
positive regulation of neuron projection development
negative regulation of neuron projection development
negative regulation of microtubule polymerization
positive regulation of microtubule depolymerization
cellular response to nerve growth factor stimulus
microtubule depolymerization
neuron projection development
regulation of cytoskeleton organization
regulation of microtubule polymerization or depolymerization
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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