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Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that transfers a sulfo moiety to and from estrone, which may control levels of estrogen receptors.
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Protein Aliases: EST-1; EST-2; EST-3; EST-6; Estrogen sulfotransferase; Estrogen sulfotransferase, isoform 3; estrogen sulfotransferase, testis isoform; Estrone sulfotransferase; ST1E1; Sulfotransferase 1E1; sulfotransferase family 1E, estrogen-preferring, member 1; sulfotransferase, estrogen preferring; Sulfotransferase, estrogen-preferring
Gene Aliases: EST; EST-1; ST1E1; STE; SULT1E1
Molecular Function: transferase