Recommended positive controls: 293T, H1299, HepG2, mouse liver.
Predicted reactivity: Mouse (82%), Rat (82%), Pig (86%), Bovine (82%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: Sulfite oxidase, mitochondrial
Gene Aliases: SO; SUOX