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Proteintech
Sam68 Polyclonal Antibody
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Product Details
10222-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human,
Mouse
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Sam68 Fusion Protein Ag0235 (200-442 aa encoded by BC000717)
Conjugate
Form
Liquid
Concentration
0.13 mg/mL
Amount
19.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
This is a rabbit polyclonal antibody raised against residues near the N-terminus of human KHDRBS1.
Immunogen sequence: KGSMRDKAK EEELRKGGDP KYAHLNMDLH VFIEVFGPPC EAYALMAHAM EEVKKFLVPD MMDDICQEQF LELSYLNGVP EPSRGRGVPV RGRGAAPPPP PVPRGRGVGP PRGALVRGTP VRGAITRGAT VTRGVPPPPT VRGAPAPRAR TAGIQRIPLP PPPAPETYEE YGYDDTYAEQ SYEGYEGYYS QSQGDSEYYD YGHGEVQDSY EAYGQDDWNG TRPSLKAPPA RPVKGAYREH PYGR (200-442 aa encoded by B C000717)
Target Information
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ34027; GAP-associated tyrosine phosphoprotein p62; GAP-associated tyrosine phosphoprotein p62 (Sam68); KH domain containing, RNA binding, signal transduction associated 1; KH domain-containing, RNA-binding, signal transduction-associated protein 1; khdrbs1; khdrbs1 {ECO:0000312|RGD:621459}; p21 Ras GTPase-activating protein-associated p62; p68; Sam68; src associated in mitosis, 68 kDa; Src-associated in mitosis 68 kDa protein; unnamed protein product
Gene Aliases: KHDRBS1; P62; p68; SAM68
UniProt ID: (Human) Q07666, (Mouse) Q60749, (Rat) Q91V33
Entrez Gene ID: (Human) 10657, (Mouse) 20218, (Rat) 117268
nucleic acid binding
DNA binding
RNA binding
mRNA binding
protein binding
poly(A) binding
poly(U) RNA binding
SH3 domain binding
protein domain specific binding
signaling adaptor activity
SH2 domain binding
identical protein binding
macromolecular complex binding
molecular function inhibitor activity
protein tyrosine kinase binding
SH3/SH2 adaptor activity
protein complex binding
poly(A) RNA binding
RNA splicing factor
G1/S transition of mitotic cell cycle
G2/M transition of mitotic cell cycle
negative regulation of transcription from RNA polymerase II promoter
regulation of alternative mRNA splicing, via spliceosome
mRNA processing
cell surface receptor signaling pathway
spermatogenesis
regulation of protein stability
regulation of apoptotic process
regulation of RNA splicing
negative regulation of transcription, DNA-templated
positive regulation of translational initiation
regulation of RNA export from nucleus
positive regulation of RNA export from nucleus
regulation of mRNA splicing, via spliceosome
T cell receptor signaling pathway
regulation of cell cycle
transcription, DNA-templated
regulation of transcription, DNA-templated
cell cycle
positive regulation of signal transduction
regulation of signal transduction
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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