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This is a rabbit polyclonal antibody raised against residues near the N-terminus of human KHDRBS1.
Immunogen sequence: KGSMRDKAK EEELRKGGDP KYAHLNMDLH VFIEVFGPPC EAYALMAHAM EEVKKFLVPD MMDDICQEQF LELSYLNGVP EPSRGRGVPV RGRGAAPPPP PVPRGRGVGP PRGALVRGTP VRGAITRGAT VTRGVPPPPT VRGAPAPRAR TAGIQRIPLP PPPAPETYEE YGYDDTYAEQ SYEGYEGYYS QSQGDSEYYD YGHGEVQDSY EAYGQDDWNG TRPSLKAPPA RPVKGAYREH PYGR (200-442 aa encoded by B C000717)
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins that functions as a soluble cofactor in importin-alpha:beta-mediated nuclear protein import. Pseudogenes of this gene are found on chromosomes 5, 6, and 14. Two transcript variants encoding different isoforms have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: FLJ34027; GAP-associated tyrosine phosphoprotein p62; GAP-associated tyrosine phosphoprotein p62 (Sam68); KH domain containing, RNA binding, signal transduction associated 1; KH domain-containing, RNA-binding, signal transduction-associated protein 1; KHDRBS1; khdrbs1 {ECO:0000312|RGD:621459}; p21 Ras GTPase-activating protein-associated p62; p68; Sam68; src associated in mitosis, 68 kDa; Src-associated in mitosis 68 kDa protein
Gene Aliases: KHDRBS1; P62; p68; SAM68
UniProt ID: (Human) Q07666, (Mouse) Q60749, (Rat) Q91V33
Entrez Gene ID: (Human) 10657, (Mouse) 20218, (Rat) 117268
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