Recommended positive controls: 293T, A431, H1299, HeLaS3, HepG2, Molt-4, Raji.
Predicted reactivity: Mouse (99%), Rat (99%), Xenopus laevis (94%), Chicken (99%), Rhesus Monkey (100%), Chimpanzee (99%), Bovine (100%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts with many other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: CDC10; CDC10 (cell division cycle 10; CDC10 (cell division cycle 10, S. cerevisiae, homolog); CDC10 protein homolog; CDC3; homolog); NBLA02942; S. cerevisiae; SEPT7A; septin 7 variant 4; Septin-7
Gene Aliases: CDC10; CDC3; NBLA02942; SEPT7; SEPT7A; SEPTIN7
UniProt ID: (Human) Q16181
Entrez Gene ID: (Human) 989