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Invitrogen
Spiramycin Polyclonal Antibody
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Product Details
PA1-75409
Product Specifications
Species Reactivity
Chemical
Host/Isotype
Sheep
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Spiramycin-BTG
Conjugate
Form
Liquid
Amount
1 mg
Purification
purified
Storage buffer
PBS, pH 7.2
Contains
0.09% sodium azide
Storage conditions
-20°C, Avoid Freeze/Thaw Cycles
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Working Concentration: 2.5 µg/mL. Sensitivity: 10 ng/mL Spiramycin produces 77% inhibition in a competitive ELISA employing Spiramycin polyclonal antibody.
Target Information
Aminoglycosides are a family of bacterial antibiotics that are used in the treatment of specific bacterial infections. They display a concentration dependent killing action and are active against a wide range of aerobic Gram-negative bacilli. Aminoglycosides are molecules that are comprised of an amino group and a sugar group. They operate by inhibiting the bacteria from producing proteins vital to its growth. More specifically, they bind to the bacterial 30S ribosomal subunit where they prevent the translocation of the peptidyl-tRNA from the A-site to the P-site, subsequently giving rise to a misreading of mRNA resulting in the inhibition of protein synthesis. This consequently results in a disruption to the integrity of the bacterial cell membrane . In addition to their use to prevent bacterial infection, aminoglycosides have been used as growth promoters in food producing animals.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Rovamycine
Disclaimer
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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