|Tested species reactivity||Human|
|Host / Isotype||Mouse / IgG1|
|Immunogen||Purified recombinant fragment of human Splunc2 (amino acids: 16-250) expressed in E. Coli.|
|Storage buffer||PBS with 0.5% proprietary stabilizer|
|Contains||0.05% sodium azide|
|Storage Conditions||Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
|Tested Applications||Dilution *|
|Flow Cytometry (Flow)||1:200 - 1:400|
|Western Blot (WB)||1:500 - 1:2000|
* Suggested working dilutions are given as a guide only. It is recommended that the user titrate the product for use in their own experiment using appropriate negative and positive controls.
MA5-17094 targets Splunc2 in FACS, pep-ELISA, and WB applications and shows reactivity with Human samples.
The MA5-17094 immunogen is purified recombinant fragment of human Splunc2 (amino acids: 16-250) expressed in E. Coli.
MA5-17094 detects Splunc2 which has a predicted molecular weight of approximately 27kDa.
SPLUNC2 is one member of PLUNC family, the gene undergoes alternative splicing using two 5' non-coding exons, suggesting that the gene is regulated by alternative promoters.multiple SPLUNC2 isoforms are found in the oral cavity and suggest that these proteins may be differentially regulated in distinct tissues where they may function in the innate immune response. Mucin plugs, mucous and intermediate cells of mucoepidermoid carcinomas were positive for LPLUNC1 and SPLUNC2, but areas composed of epidermoid and clear cells were negative for all PLUNCs. Papillary cystadenocarcinoma was positive for all PLUNCs.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.