Immunogen sequence: MASSDIQVKE LEKRASGQAF ELILSPRSKE SVPEFPLSPP KKKDLSLEEI QKKLEAAEER RKSHEAEVLK QLAEKREHEK EVLQKAIEEN NNFSKMAEEK LTHKMEANKE NREAQMAAKL ERLREKDKHI EEVRKNKESK DPADETEAD; Positive Samples: SW620, U-937, Jurkat; Cellular Location: Cytoplasm, cytoskeleton
Stathmin 1 belongs to the stathmin family of genes. It encodes a ubiquitous cytosolic phosphoprotein proposed to function as an intracellular relay integrating regulatory signals of the cellular environment. Stathmin 1 is involved in the regulation of the microtubule filament system by destabilizing microtubules. It prevents assembly and promotes disassembly of microtubules. Multiple transcript variants encoding different isoforms have been found for this gene.
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Protein Aliases: Leukemia-associated phosphoprotein p18; Metablastin; Oncoprotein 18; Op18; phosphoprotein 19; Phosphoprotein p19; pp17; pp19; Prosolin; Protein Pr22; Stathmin; stathmin 1/oncoprotein 18; testicular tissue protein Li 189; transmembrane protein C1orf215
Gene Aliases: C1orf215; Lag; LAP18; OP18; PP17; PP19; PR22; SMN; STMN1
UniProt ID: (Human) P16949
Entrez Gene ID: (Human) 3925