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Product Details
13893-1-AP
| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
1:500-1:2400 | - |
Immunohistochemistry (Paraffin) (IHC (P)) |
1:20-1:200 | - |
Immunocytochemistry (ICC/IF) |
1:50-1:500 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human, Mouse, Rat |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Synaptojanin 2 Fusion Protein Ag4855 (1147-1496 aa encoded by BC043277) |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.41 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.3, with 50% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
-20°C |
Product Specific Information
Immunogen sequence: APQQPPKAR TGISKPYNVK QIKTTNAQEA EAAIRCLLEA RGGASEEALS AVAPRDLEAS SEPEPTPGAA KPETPQAPPL LPRRPPPRVP AIKKPTLRRT GKPLSPEEQF EQQTVHFTIG PPETSVEAPP VVTAPRVPPV PKPRTFQPGK AAERPSHRKP ASDEAPPGAG ASVPPPLEAP PLVPKVPPRR KKSAPAAFHL QVLQSNSQLL QGLTYNSSDS PSGHPPAAGT VFPQGDFLST SSATSPDSDG TKAMKPEAAP LLGDYQDPFW NLLHHPKLLN NTWLSKSSDP LDSGTRSPKR DPIDPVSAGA SAAKAELPPD HGHKTLGHWV TISDQEKRTA LQVFDPLAKT (1147-1496 aa encoded by BC043277)
Target Information
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: inositol phosphate 5'-phosphatase 2; inositol polyphosphate-5-phosphatase H; phosphoinositide 5-phosphatase; Synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2; Synaptojanin-2
Gene Aliases: AI481647; INPP5H; KIAA0348; mKIAA0348; SJ2; SYNJ2
UniProt ID: (Human) O15056, (Mouse) Q9D2G5, (Rat) O55207
Entrez Gene ID: (Human) 8871, (Mouse) 20975, (Rat) 84018
Molecular Function:
phosphatase
nucleotide binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
protein binding
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
nucleic acid binding
inositol-polyphosphate 5-phosphatase activity
hydrolase activity
SH3 domain binding
PDZ domain binding
phosphoric ester hydrolase activity
phosphatidylinositol monophosphate phosphatase activity
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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