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Proteintech
Synaptojanin 2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product Details
13893-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Synaptojanin 2 Fusion Protein Ag4855 (1147-1496 aa encoded by BC043277)
Conjugate
Unconjugated
Unconjugated
Unconjugated
Form
Liquid
Concentration
0.41 mg/mL
Amount
61.5 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: APQQPPKAR TGISKPYNVK QIKTTNAQEA EAAIRCLLEA RGGASEEALS AVAPRDLEAS SEPEPTPGAA KPETPQAPPL LPRRPPPRVP AIKKPTLRRT GKPLSPEEQF EQQTVHFTIG PPETSVEAPP VVTAPRVPPV PKPRTFQPGK AAERPSHRKP ASDEAPPGAG ASVPPPLEAP PLVPKVPPRR KKSAPAAFHL QVLQSNSQLL QGLTYNSSDS PSGHPPAAGT VFPQGDFLST SSATSPDSDG TKAMKPEAAP LLGDYQDPFW NLLHHPKLLN NTWLSKSSDP LDSGTRSPKR DPIDPVSAGA SAAKAELPPD HGHKTLGHWV TISDQEKRTA LQVFDPLAKT (1147-1496 aa encoded by BC043277)
Target Information
The gene is a member of the inositol-polyphosphate 5-phosphatase family. The encoded protein interacts with the ras-related C3 botulinum toxin substrate 1, which causes translocation of the encoded protein to the plasma membrane where it inhibits clathrin-mediated endocytosis. Alternative splicing results in multiple transcript variants.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: inositol phosphate 5'-phosphatase 2; inositol polyphosphate 5'-phosphatase; inositol polyphosphate-5-phosphatase H; phosphatidyl inositol phosphatase; phosphoinositide 5-phosphatase; phosphoinositide phosphatase; synaptic inositol 1,4,5-trisphosphate 5-phosphatase 2; synaptic inositol-1,4,5-trisphosphate 5-phosphatase 2; synaptojanin-2; unnamed protein product
Gene Aliases: INPP5H; mKIAA0348; SJ2
UniProt ID: (Human) O15056, (Mouse) Q9D2G5, (Rat) O55207
Entrez Gene ID: (Human) 8871, (Mouse) 20975, (Rat) 84018
nucleic acid binding
RNA binding
phosphatidylinositol-3-phosphatase activity
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
protein binding
phosphatase activity
phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity
phosphatidylinositol phosphate 4-phosphatase activity
phosphatidylinositol-4-phosphate phosphatase activity
phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity
phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity
inositol-1,4,5-trisphosphate 5-phosphatase activity
inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity
phosphatidylinositol phosphate phosphatase activity
SH3 domain binding
PDZ domain binding
phosphatidylinositol phosphate 5-phosphatase activity
phosphatidylinositol monophosphate phosphatase activity
inositol phosphate phosphatase activity
receptor-mediated endocytosis
phosphatidylinositol metabolic process
phosphatidylinositol dephosphorylation
clathrin coat assembly
synaptic vesicle endocytosis
inositol phosphate catabolic process
phosphatidylinositol biosynthetic process
phosphatidylinositol-3-phosphate biosynthetic process
membrane organization
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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