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Synaptotagmin 2 Polyclonal Antibody
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FIGURE: 1 / 21
Synaptotagmin 2 Antibody (OSS00023W-100UL) in IHC (P)
IHC-P on paraffin sections of mouse spinal cord. The animal was perfused using Autoperfuser at a pressure of 130 mmHg with 300 mL 4% FA before being processed for paraffin embedding. HIER: Tris-EDTA, pH 9 for 20 min using Thermo PT Module. Blocking: 0.2% LFDM in TBST filtered thru 0.2 µm. Detection was done using Novolink HRP polymer from Leica following manufacturers instructions; DAB chromogen: Candela DA... View More
Product Details
OSS00023W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Non-human primate,
Rat
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from rat Synaptotagmin2 conjugated to blue carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: SYTII.
Target Information
Synaptotagmins, like SYT2, are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (Hilbush and Morgan, 1994 [PubMed 8058779]).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Inositol polyphosphate-binding protein; IP4-binding protein; synaptotagmin 2; Synaptotagmin II; Synaptotagmin-2; SytII; unnamed protein product
Gene Aliases: CMS7; CMS7A; CMS7B; mKIAA4194; MYSPC; R74640; RATSYNII; SYNII; SYT2; SytII
UniProt ID: (Human) Q8N9I0, (Rat) P29101, (Mouse) P46097
Entrez Gene ID: (Human) 127833, (Rat) 24805, (Mouse) 20980
vesicle-mediated transport
regulation of calcium ion-dependent exocytosis
cell differentiation
calcium-dependent activation of synaptic vesicle fusion
positive regulation of dendrite extension
regulation of synaptic vesicle exocytosis
transport
synaptic vesicle exocytosis
neurotransmitter secretion
synaptic vesicle endocytosis
calcium ion-regulated exocytosis of neurotransmitter
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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