Proteintech

Syntaxin 3 Polyclonal Antibody

View all (17) Syntaxin 3 antibodies

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Syntaxin 3 Antibody in Western Blot (WB) — Human blood tissue were subjected to SDS PAGE followed by western blot with 15556-1-AP (Syntaxin 3 antibody) at dilution of 1:700 incubated at room temperature for 1.5 hours.

Syntaxin 3 Antibody in Western Blot (WB) — Neuro-2a cells were subjected to SDS PAGE followed by western blot with 15556-1-AP (Syntaxin 3 antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Syntaxin 3 Antibody in Western Blot (WB) — SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 15556-1-AP ( Syntaxin 3 antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours.

Syntaxin 3 Antibody in Immunoprecipitation (IP) — IP result of anti-Syntaxin 3 (IP: 15556-1-AP, 4 µg; Detection: 15556-1-AP 1:1000) with SH-SY5Y cells lysate 3600 µg.

Product Details

15556-1-AP

Applications	Tested Dilution	Publications
Western Blot (WB)	1:500-1:2,000	View 3 publications 3 publications
Immunohistochemistry (Paraffin) (IHC (P))	1:200	-
Immunocytochemistry (ICC/IF)	Assay-dependent	View 3 publications 3 publications
Immunoprecipitation (IP)	0.5-4.0 µg	-

Product Specifications
Species Reactivity	Human, Mouse, Rat
Published species	Human, Mouse
Host/Isotype	Rabbit / IgG
Class	Polyclonal
Type	Antibody
Immunogen	Syntaxin 3 Fusion Protein Ag7925 (1-264 aa encoded by BC007405) View immunogen
Conjugate	Unconjugated
Form	Liquid
Concentration	0.3 mg/mL
Purification	Antigen affinity chromatography
Storage buffer	PBS, pH 7.3, with 50% glycerol
Contains	0.02% sodium azide
Storage conditions	-20°C

Product Specific Information

Immunogen sequence: MKDRLEQLK AKQLTQDDDT DAVEIAIDNT AFMDEFFSEI EETRLNIDKI SEHVEEAKKL YSIILSAPIP EPKTKDDLEQ LTTEIKKRAN NVRNKLKSME KHIEEDEVRS SADLRIRKSQ HSVLSRKFVE VMTKYNEAQV DFRERSKGRI QRQLEITGKK TTDEELEEML ESGNPAIFTS GIIDSQISKQ ALSEIEGRHK DIVRLESSIK ELHDMFMDIA MLVENQGEML DNIELNVMHT VDHVEKARDE TKKAVKYQSQ ARKKL (1-264 aa encoded by BC007405)

Target Information

The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors.

Frontiers in molecular neuroscience

Brooks C,Murphy J,Belcastro M,Heller D,Kolandaivelu S,Kisselev O,Sokolov M

Tue Sep 29 00:00:00 EDT 2020

C2 Domains of Munc13-4 Are Crucial for Ca²⁺-Dependent Degranulation and Cytotoxicity in NK Cells.

Journal of immunology (Baltimore, Md. : 1950)

Bin NR,Ma K,Tien CW,Wang S,Zhu D,Park S,Turlova E,Sugita K,Shirakawa R,van der Sluijs P,Horiuchi H,Sun HS,Monnier PP,Gaisano HY,Sugita S

Sun Jul 15 00:00:00 EDT 2018

BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.

PLoS genetics

Hsu Y,Garrison JE,Kim G,Schmitz AR,Searby CC,Zhang Q,Datta P,Nishimura DY,Seo S,Sheffield VC

Sun Oct 01 00:00:00 EDT 2017

Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin.

The Journal of biological chemistry

Aerbajinai W,Liu L,Zhu J,Kumkhaek C,Chin K,Rodgers GP

Fri Apr 15 00:00:00 EDT 2016

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.

Proceedings of the National Academy of Sciences of the United States of America

Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S

Tue Aug 11 00:00:00 EDT 2015

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.

Proceedings of the National Academy of Sciences of the United States of America

Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S

Tue Aug 11 00:00:00 EDT 2015

Bioinformatics

Protein Aliases: syntaxin 3A; Syntaxin-3

Gene Aliases: STX3; STX3A; Syn-3

UniProt ID: (Human) Q13277, (Mouse) Q64704, (Rat) Q08849

Entrez Gene ID: (Human) 6809, (Mouse) 20908, (Rat) 81802

Molecular Function: SNARE protein

intracellular protein transport positive regulation of cell proliferation synaptic vesicle docking neuron projection development synaptic vesicle fusion to presynaptic active zone membrane positive regulation of cell adhesion vesicle docking positive regulation of chemotaxis long-term synaptic potentiation positive regulation of protein localization to plasma membrane positive regulation of protein localization to cell surface transport neurotransmitter transport exocytosis vesicle-mediated transport membrane fusion intracellular transport

Process(es)

SNARE binding SNAP receptor activity protein binding arachidonic acid binding