Proteintech

Syntaxin 3 Polyclonal Antibody

Syntaxin 3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))

FIGURE: 1 / 6

Syntaxin 3 Antibody (15556-1-AP) in IHC (P)

Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using (Product # 15556-1-AP) (Syntaxin 3 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

Syntaxin 3 Antibody in Western Blot (WB)

Syntaxin 3 Antibody in Immunoprecipitation (IP)

Product Image Gallery

Product Details

15556-1-AP

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

View 8 publications 8 publications

Immunohistochemistry (IHC)

View 2 publications 2 publications

Immunohistochemistry (Paraffin) (IHC (P))

1:200

Immunocytochemistry (ICC/IF)

Assay-dependent

View 6 publications 6 publications

Immunoprecipitation (IP)

0.5-4.0 µg

View 2 publications 2 publications

Product Specifications

Species Reactivity

Human, Mouse, Rat

Published species

Human, Mouse

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Syntaxin 3 Fusion Protein Ag7925 (1-264 aa encoded by BC007405)

View immunogen

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice (domestic); Dry ice (international)

Product Specific Information

Immunogen sequence: MKDRLEQLK AKQLTQDDDT DAVEIAIDNT AFMDEFFSEI EETRLNIDKI SEHVEEAKKL YSIILSAPIP EPKTKDDLEQ LTTEIKKRAN NVRNKLKSME KHIEEDEVRS SADLRIRKSQ HSVLSRKFVE VMTKYNEAQV DFRERSKGRI QRQLEITGKK TTDEELEEML ESGNPAIFTS GIIDSQISKQ ALSEIEGRHK DIVRLESSIK ELHDMFMDIA MLVENQGEML DNIELNVMHT VDHVEKARDE TKKAVKYQSQ ARKKL (1-264 aa encoded by BC007405)

Target Information

The gene is a member of the syntaxin family. The encoded protein is targeted to the apical membrane of epithelial cells where it forms clusters and is important in establishing and maintaining polarity necessary for protein trafficking involving vesicle fusion and exocytosis. Alternative splicing results in multiple transcript variants.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

Product References

Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy.

bioRxiv : the preprint server for biology

Haggerty KN,Eshelman SC,Sexton LA,Frimpong E,Rogers LM,Agosto MA,Robichaux MA

Fri Apr 21 00:00:00 UTC 2023

Mapping rhodopsin trafficking in rod photoreceptors with quantitative super-resolution microscopy.

bioRxiv : the preprint server for biology

Haggerty KN,Eshelman SC,Sexton LA,Frimpong E,Rogers LM,Agosto MA,Robichaux MA

Fri Apr 21 00:00:00 UTC 2023

circMRPS35 promotes malignant progression and cisplatin resistance in hepatocellular carcinoma.

Molecular therapy : the journal of the American Society of Gene Therapy

Li P,Song R,Yin F,Liu M,Liu H,Ma S,Jia X,Lu X,Zhong Y,Yu L,Li X,Li X

Wed Jan 05 00:00:00 UTC 2022

circMRPS35 promotes malignant progression and cisplatin resistance in hepatocellular carcinoma.

Molecular therapy : the journal of the American Society of Gene Therapy

Li P,Song R,Yin F,Liu M,Liu H,Ma S,Jia X,Lu X,Zhong Y,Yu L,Li X,Li X

Wed Jan 05 00:00:00 UTC 2022

Photoreceptor cilia, in contrast to primary cilia, grant entry to a partially assembled BBSome.

Human molecular genetics

Hsu Y,Seo S,Sheffield VC

Thu Mar 25 00:00:00 UTC 2021

SNAP25/syntaxin4/VAMP2/Munc18-1 Complexes in Spinal Dorsal Horn Contributed to Inflammatory Pain.

Neuroscience

Duan XL,Guo Z,He YT,Li YX,Liu YN,Bai HH,Li HL,Hu XD,Suo ZW

Sun Mar 01 00:00:00 UTC 2020

Syntaxin-3 is dispensable for basal neurotransmission and synaptic plasticity in postsynaptic hippocampal CA1 neurons.

Scientific reports

Shi S,Ma K,Bin NR,Harada H,Xie X,Huang M,Liu H,Lee S,Wang XF,Adachi R,Monnier PP,Zhang L,Sugita S

Mon Jan 20 00:00:00 UTC 2020

The absence of BBSome function decreases synaptogenesis and causes ectopic synapse formation in the retina.

Scientific reports

Hsu Y,Garrison JE,Seo S,Sheffield VC

Wed May 20 00:00:00 UTC 2020

The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.

The Journal of biological chemistry

Datta P,Hendrickson B,Brendalen S,Ruffcorn A,Seo S

Fri Dec 13 00:00:00 UTC 2019

The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.

The Journal of biological chemistry

Datta P,Hendrickson B,Brendalen S,Ruffcorn A,Seo S

Fri Dec 13 00:00:00 UTC 2019

The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.

The Journal of biological chemistry

Datta P,Hendrickson B,Brendalen S,Ruffcorn A,Seo S

Fri Dec 13 00:00:00 UTC 2019

Structural and Functional Analysis of the CAPS SNARE-Binding Domain Required for SNARE Complex Formation and Exocytosis.

Cell reports

Zhou H,Wei Z,Wang S,Yao D,Zhang R,Ma C

Tue Mar 19 00:00:00 UTC 2019

Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors.

Frontiers in molecular neuroscience

Brooks C,Murphy J,Belcastro M,Heller D,Kolandaivelu S,Kisselev O,Sokolov M

Wed Aug 16 00:00:00 UTC 2023

Farnesylation of the Transducin G Protein Gamma Subunit Is a Prerequisite for Its Ciliary Targeting in Rod Photoreceptors.

Frontiers in molecular neuroscience

Brooks C,Murphy J,Belcastro M,Heller D,Kolandaivelu S,Kisselev O,Sokolov M

Wed Aug 16 00:00:00 UTC 2023

C2 Domains of Munc13-4 Are Crucial for Ca²⁺-Dependent Degranulation and Cytotoxicity in NK Cells.

Journal of immunology (Baltimore, Md. : 1950)

Bin NR,Ma K,Tien CW,Wang S,Zhu D,Park S,Turlova E,Sugita K,Shirakawa R,van der Sluijs P,Horiuchi H,Sun HS,Monnier PP,Gaisano HY,Sugita S

Sun Jul 15 00:00:00 UTC 2018

C2 Domains of Munc13-4 Are Crucial for Ca²⁺-Dependent Degranulation and Cytotoxicity in NK Cells.

Journal of immunology (Baltimore, Md. : 1950)

Bin NR,Ma K,Tien CW,Wang S,Zhu D,Park S,Turlova E,Sugita K,Shirakawa R,van der Sluijs P,Horiuchi H,Sun HS,Monnier PP,Gaisano HY,Sugita S

Sun Jul 15 00:00:00 UTC 2018

BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.

PLoS genetics

Hsu Y,Garrison JE,Kim G,Schmitz AR,Searby CC,Zhang Q,Datta P,Nishimura DY,Seo S,Sheffield VC

Sun Oct 01 00:00:00 UTC 2017

BBSome function is required for both the morphogenesis and maintenance of the photoreceptor outer segment.

PLoS genetics

Hsu Y,Garrison JE,Kim G,Schmitz AR,Searby CC,Zhang Q,Datta P,Nishimura DY,Seo S,Sheffield VC

Sun Oct 01 00:00:00 UTC 2017

Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin.

The Journal of biological chemistry

Aerbajinai W,Liu L,Zhu J,Kumkhaek C,Chin K,Rodgers GP

Fri Apr 15 00:00:00 UTC 2016

Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin.

The Journal of biological chemistry

Aerbajinai W,Liu L,Zhu J,Kumkhaek C,Chin K,Rodgers GP

Fri Apr 15 00:00:00 UTC 2016

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.

Proceedings of the National Academy of Sciences of the United States of America

Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S

Tue Aug 11 00:00:00 UTC 2015

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.

Proceedings of the National Academy of Sciences of the United States of America

Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S

Tue Aug 11 00:00:00 UTC 2015

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.

Proceedings of the National Academy of Sciences of the United States of America

Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S

Tue Aug 11 00:00:00 UTC 2015

Accumulation of non-outer segment proteins in the outer segment underlies photoreceptor degeneration in Bardet-Biedl syndrome.

Proceedings of the National Academy of Sciences of the United States of America

Datta P,Allamargot C,Hudson JS,Andersen EK,Bhattarai S,Drack AV,Sheffield VC,Seo S

Tue Aug 11 00:00:00 UTC 2015

Bioinformatics

Protein Aliases: syntaxin 3A; Syntaxin-3

View more View less

Gene Aliases: STX3; STX3A; Syn-3

View more View less

UniProt ID: (Human) Q13277, (Mouse) Q64704, (Rat) Q08849

View more View less

Entrez Gene ID: (Human) 6809, (Mouse) 20908, (Rat) 81802

View more View less

Function(s)

SNARE binding SNAP receptor activity protein binding arachidonic acid binding SNARE protein

Process(es)

intracellular protein transport positive regulation of cell proliferation synaptic vesicle docking neuron projection development synaptic vesicle fusion to presynaptic active zone membrane positive regulation of cell adhesion vesicle docking positive regulation of chemotaxis long-term synaptic potentiation positive regulation of protein localization to plasma membrane positive regulation of protein localization to cell surface transport neurotransmitter transport exocytosis vesicle-mediated transport membrane fusion intracellular transport

Performance Guarantee

If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*

Learn more

Syntaxin 3 Polyclonal Antibody

Syntaxin 3 Antibody (15556-1-AP) in IHC (P)

Product Details

15556-1-AP

Western Blot (WB)

Immunohistochemistry (IHC)

Immunohistochemistry (Paraffin) (IHC (P))

Immunocytochemistry (ICC/IF)

Immunoprecipitation (IP)

Species Reactivity

Published species

Host/Isotype

Class

Type

Immunogen

Conjugate

Form

Concentration

Purification

Storage buffer

Contains

Storage conditions

Shipping conditions

Product Specific Information

Target Information

Bioinformatics

Performance Guarantee

We're here to help

Your items have has been added!