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Syntaxin 4 Polyclonal Antibody
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Product Details
OSS00173W-100UL
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ Ig
Class
Polyclonal
Type
Antibody
Immunogen
A synthetic peptide from n-terminal region of human Syntaxin-4 (STX4A, STX4) conjugated to an immunogenic carrier protein was used as the antigen
Conjugate
Form
Lyophilized
Concentration
Conc. Not Determined
Storage buffer
whole serum
Contains
no preservative
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability.
Shipping conditions
Ambient (domestic); Wet ice (international)
Product Specific Information
Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Specificity of this antibody: Syntaxin-4.
Target Information
STX4 is a plasma membrane t-SNARE that mediates docking of transport vesicles.STX4 is necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, STX4 may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STX4 may also play a role in docking of synaptic vesicles at presynaptic active zones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Renal carcinoma antigen NY-REN-31; STX4A; syntaxin 4A (placental); Syntaxin-4; unnamed protein product
Gene Aliases: DFNB123; p35-2; STX4; STX4A
UniProt ID: (Human) Q12846
Entrez Gene ID: (Human) 6810
positive regulation of immunoglobulin production
neurotransmitter transport
intracellular protein transport
exocytosis
vesicle fusion
sensory perception of sound
positive regulation of cell proliferation
vesicle-mediated transport
regulation of exocytosis
positive regulation of cell migration
protein localization to cell surface
cellular response to oxidative stress
SNARE complex assembly
positive regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of catalytic activity
positive regulation of eosinophil degranulation
positive regulation of cell adhesion
vesicle docking
organelle fusion
positive regulation of chemotaxis
long-term synaptic potentiation
membrane organization
cellular response to interferon-gamma
regulation of postsynaptic membrane neurotransmitter receptor levels
regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of protein localization to plasma membrane
cornified envelope assembly
positive regulation of protein localization to cell surface
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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