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Invitrogen
Syntaxin 4 Polyclonal Antibody
Advanced Verification
This Antibody was verified by Knockdown to ensure that the antibody binds to the antigen stated.
Product Details
PA5-51560
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human STX4. Recombinant protein control fragment (Product #RP-95939).
Conjugate
Form
Liquid
Concentration
0.3 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2648059
Product Specific Information
Immunogen sequence: MRDRTHELRQ GDDSSDEEDK ERVALVVHPG TARLGSPDEE FFHKVRTIRQ TIVKLGNKVQ ELEKQQVTIL ATPLPEESMK QELQNLRDEI KQLGREIRLQ LKAIEPQKEE ADENYNSVNT RMRKTQHGVL SQQFVELINK CNSMQSE^M
^M
Highest antigen sequence identity to the following orthologs: Mouse - 86%, Rat - 86%.
Target Information
STX4 is a plasma membrane t-SNARE that mediates docking of transport vesicles.STX4 is necessary for the translocation of SLC2A4 from intracellular vesicles to the plasma membrane. Together with STXB3 and VAMP2, STX4 may also play a role in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. STX4 may also play a role in docking of synaptic vesicles at presynaptic active zones.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Renal carcinoma antigen NY-REN-31; syntaxin 4A (placental); Syntaxin-4
Gene Aliases: p35-2; STX4; STX4A
UniProt ID: (Human) Q12846
Entrez Gene ID: (Human) 6810
intracellular protein transport
post-Golgi vesicle-mediated transport
positive regulation of cell proliferation
regulation of exocytosis
positive regulation of cell migration
synaptic vesicle fusion to presynaptic active zone membrane
response to hydroperoxide
SNARE complex assembly
positive regulation of insulin secretion involved in cellular response to glucose stimulus
positive regulation of catalytic activity
positive regulation of eosinophil degranulation
positive regulation of cell adhesion
vesicle docking
organelle fusion
positive regulation of chemotaxis
positive regulation of immunoglobulin secretion
long-term synaptic potentiation
positive regulation of establishment of protein localization to plasma membrane
regulation of extrinsic apoptotic signaling pathway via death domain receptors
positive regulation of protein localization to plasma membrane
positive regulation of protein localization to cell surface
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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