Immunogen sequence: ISSPGMSGHR QGHDSLEHDE LREIFNDLSS SSEDEDETQH QDEEDINIID TEEDLERQLQ DKLNESDEQH QENEGTNQLV MGIQKQIDNM KGKLQETQDR AKRQEDLIMK VENLALKN
Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 92%.
The intronless gene for this transcription coactivator is located between the protocadherin beta and gamma gene clusters on chromosome 5. The protein encoded by this gene is a component of the TFIID protein complex, a complex which binds to the TATA box in class II promoters and recruits RNA polymerase II and other factors. This particular subunit interacts with the largest TFIID subunit, as well as multiple transcription activators. The protein is required for transcription by promoters targeted by RNA polymerase II. The general transcription factor, TFIID, consists of the TATA-binding protein (TBP) associated with a series of TBP-associated factors (TAFs) that together participate in the assembly of the transcription preinitiation complex.
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Protein Aliases: RNA polymerase II TBP-associated factor subunit F; TAF(II)55; TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa; TAFII-55; TATA box binding protein (TBP)-associated factor, RNA polymerase II, F, 55kD; TATA box binding protein associated factor 7; TBP-associated factor F; transcription factor IID subunit TAFII55; Transcription initiation factor TFIID 55 kDa subunit; Transcription initiation factor TFIID subunit 7; transcription initiation factor TFIID, 55 kDa subunit
Gene Aliases: TAF2F; TAF7; TAFII55
UniProt ID: (Human) Q15545
Entrez Gene ID: (Human) 6879