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Invitrogen
TAFA3 Polyclonal Antibody
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Product Details
PA5-63210
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human TAFA3. Recombinant protein control fragment (Product #RP-101557).
Conjugate
Form
Liquid
Concentration
0.1 mg/mL
Amount
10 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: AALQPPTATV LVQQGTCEVI A
Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 86%.
Target Information
The TAFA3 gene encodes a protein that is part of the TAFA family of chemokine-like proteins, involved in modulating immune responses and inflammatory processes. TAFA3 is particularly implicated in the regulation of neuroinflammatory and neuroprotective activities in the central nervous system. It functions as a signaling molecule that can influence cell survival, proliferation, and migration, contributing to homeostasis in neural tissue and promoting recovery following injury. TAFA3 has been studied for its role in neuroprotection, where it helps shield neurons from damage caused by oxidative stress and inflammatory stimuli, making it significant in neurodegenerative conditions. Apart from its neuroprotective capabilities, TAFA3 may also be involved in the systemic modulation of inflammation, affecting immune cell trafficking and responses. Research into TAFA3 continues to unveil its multifaceted role in health and disease, highlighting potential therapeutic avenues for targeting this protein in conditions characterized by excessive inflammation or neurodegeneration.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: Chemokine-like protein TAFA-3; family with sequence similarity 19 (chemokine (C-C motif)-like), member A3; family with sequence similarity 19 member A3, C-C motif chemokine like; protein FAM19A3
Gene Aliases: FAM19A3; TAFA-3; TAFA3
UniProt ID: (Human) Q7Z5A8
Entrez Gene ID: (Human) 284467
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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