|Immunohistochemistry (Paraffin) (IHC (P))||1:100-1:1000|
|Western Blot (WB)||1:500-1:3000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||Synthetic peptide corresponding to a region within amino acids 129 and 223 of Human TAS1R1|
|Purification||Antigen affinity chromatography|
|Storage buffer||0.1M tris glycine, pH 7, with 20% glycerol|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
PA5-30597 targets TAS1R1 in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-30597 immunogen is synthetic peptide corresponding to a region within amino acids 129 and 223 of Human TAS1R1.
The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding several different isoforms have been found for this gene.
Protein Aliases: G protein-coupled receptor 70; G-protein coupled receptor 70; GPR70; seven transmembrane helix receptor; T1R1; Taste receptor type 1 member 1; taste receptor, type 1, member 1; TR1
Gene Aliases: GM148; GPR70; T1R1; TAS1R1; TR1
UniProt ID: (Human) Q7RTX1
Entrez Gene ID: (Human) 80835