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Proteintech
TBCD Polyclonal Antibody
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Product Details
14867-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human,
Mouse,
Rat
Published species
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TBCD Fusion Protein Ag6310 (1-270 aa encoded by BC003094)
Conjugate
Form
Liquid
Concentration
0.19 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: MALSDEPAA GGPEEEAEDE TLAFGAALEA FGESAETRAL LGRLREVHGG GAEREVALER FRVIMDKYQE QPHLLDPHLE WMMNLLLDIV QDQTSPASLV HLAFKFLYII TKVRGYKTFL RLFPHEVADV EPVLDLVTIQ NPKDHEAWET RYMLLLWLSV TCLIPFDFSR LDGNLLTQPG QARMSIMDRI LQIAESYLIV SDKARDAAAV LVSRFITRPD VKQSKMAEFL DWSLCNLARS SFQTMQGVIT MDGTLQALAQ IFKHGKREDC L (1-270 aa encoded by BC003094)
Target Information
Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: Beta-tubulin cofactor D; SSD-1; tfcD; Tubulin-folding cofactor D; Tubulin-specific chaperone D
Gene Aliases: 2310057L06Rik; A030005L14Rik; KIAA0988; mKIAA0988; PP1096; SSD-1; SSD1; TBCD; TFCD
UniProt ID: (Human) Q9BTW9, (Mouse) Q8BYA0
Entrez Gene ID: (Human) 6904, (Rat) 100361417, (Mouse) 108903
protein folding
tubulin complex assembly
post-chaperonin tubulin folding pathway
negative regulation of cell-substrate adhesion
negative regulation of microtubule polymerization
adherens junction assembly
positive regulation of GTPase activity
bicellular tight junction assembly
microtubule cytoskeleton organization
obsolete tubulin complex biogenesis
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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