|Western Blot (WB)||1:1000|
|Tested Species reactivity||Human|
|Host / Isotype||Rabbit / IgG|
|Immunogen||KLH conjugated synthetic peptide between 364-392 amino acids from the central region of human TBCE|
|Purification||Antigen affinity chromatography|
|Contains||0.09% sodium azide|
|Storage conditions||-20° C, Avoid Freeze/Thaw Cycles|
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: HRD; hypoparathyroidism, growth and mental retardation, and dysmorphism; KCS; KCS1; Kenny-Caffey syndrome; pac2; Tubulin-folding cofactor E; Tubulin-specific chaperone E
Gene Aliases: HRD; KCS; KCS1; pac2; TBCE
UniProt ID: (Human) Q15813
Entrez Gene ID: (Human) 6905
Molecular Function: chaperone
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