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| Applications | Tested Dilution | Publications |
|---|---|---|
Western Blot (WB) |
0.04-0.4 µg/mL | - |
Immunohistochemistry (IHC) |
1:500-1:1,000 | - |
| Product Specifications | |
|---|---|
Species Reactivity |
Human |
Host/Isotype |
Rabbit / IgG |
Class |
Polyclonal |
Type |
Antibody |
Immunogen |
Recombinant protein corresponding to Human TBCE |
Conjugate |
Unconjugated |
Form |
Liquid |
Concentration |
0.1 mg/mL |
Purification |
Antigen affinity chromatography |
Storage buffer |
PBS, pH 7.2, with 40% glycerol |
Contains |
0.02% sodium azide |
Storage conditions |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
RRID |
AB_2648288 |
Immunogen sequence: ERGKHDGSHE GTVYFKCRHP TGGSFIRPNK VNFGTDFLTA IKNRYVLEDG PEEDRKEQIV TIGNKPVETI GFDSIMKQQS QLSKLQEVSL RNCAVSCAGE
Highest antigen sequence identity to the following orthologs: Mouse - 71%, Rat - 71%.
Cofactor E is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Protein Aliases: hypoparathyroidism, growth and mental retardation, and dysmorphism; Tubulin-folding cofactor E; Tubulin-specific chaperone E
Gene Aliases: HRD; KCS; KCS1; pac2; TBCE
UniProt ID: (Human) Q15813
Entrez Gene ID: (Human) 6905
Molecular Function:
chaperone
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