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Proteintech
TERF1 Polyclonal Antibody
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Product Details
11899-1-AP
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
TERF1 Fusion Protein Ag2491 (118-419 aa encoded by BC029378)
Conjugate
Form
Liquid
Concentration
0.21 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.3, with 50% glycerol
Contains
0.02% sodium azide
Storage conditions
-20°C
Shipping conditions
Wet ice (domestic); Dry ice (international)
Product Specific Information
Immunogen sequence: CQLRTIYIC QFLTRIAAGK TLDAQFENDE RITPLESALM IWGSIEKEHD KLHEEIQNLI KIQAIAVCME NGNFKEAEEV FERIFGDPNS HMPFKSKLLM IISQKDTFHS FFQHFSYNHM MEKIKSYVNY VLSEKSSTFL MKAAAKVVES KRTRTITSQD KPSGNDVEME TEANLDTRKR SHKNLFLSKL QHGTQQQDLN KKERRVGTPQ STKKKKESRR ATESRIPVSK SQPVTPEKHR ARKRQAWLWE EDKNLRSGVR KYGEGNWSKI LLHYKFNNRT SVMLKDRWRT MKKLKLISSD SED (118-419 aa encoded by BC029378)
Target Information
This gene encodes a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell cycle and functions as an inhibitor of telomerase, acting in cis to limit the elongation of individual chromosome ends. The protein structure contains a C-terminal Myb motif, a dimerization domain near its N-terminus and an acidic N-terminus. Two transcripts of this gene are alternatively spliced products.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Bioinformatics
Protein Aliases: FLJ41416; NIMA-interacting protein 2; Telomeric protein Pin2/TRF1; telomeric repeat binding factor (NIMA-interacting) 1; Telomeric repeat-binding factor 1; TTAGGG repeat-binding factor 1
Gene Aliases: hTRF1-AS; PIN2; t-TRF1; TERF1; TRBF1; TRF; TRF1
UniProt ID: (Human) Q93029
Entrez Gene ID: (Human) 7013
telomere maintenance
telomere maintenance via telomerase
mitotic nuclear division
negative regulation of DNA replication
telomere capping
telomeric loop formation
negative regulation of telomere maintenance via telomerase
negative regulation of telomere maintenance via semi-conservative replication
response to drug
meiotic telomere clustering
cell division
negative regulation of telomerase activity
positive regulation of telosome assembly
negative regulation of establishment of protein localization to telomere
negative regulation of establishment of RNA localization to telomere
negative regulation of establishment of macromolecular complex localization to telomere
Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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